Smouldering myeloma

Smouldering Myeloma

Smouldering myeloma (pronunciation: smoul-der-ing mye-lo-ma), also known as indolent myeloma or asymptomatic myeloma, is a slow-growing type of multiple myeloma. The term "smouldering" is derived from the Latin word "smolder" meaning "to burn without flame", which metaphorically describes the slow progression of this disease.

Definition

Smouldering myeloma is a plasma cell neoplasm characterized by the presence of abnormal plasma cells in the bone marrow and a high level of monoclonal protein in the blood. However, unlike active multiple myeloma, it does not cause any symptoms or complications.

Diagnosis

Diagnosis of smouldering myeloma is typically made through a combination of blood tests, urine tests, and a bone marrow biopsy. The presence of 10% or more plasma cells in the bone marrow or a serum monoclonal protein level of 3 g/dL or more is indicative of smouldering myeloma.

Treatment

Treatment for smouldering myeloma is usually watchful waiting, as the disease progresses slowly and does not cause symptoms. However, if the disease shows signs of progression to active multiple myeloma, treatment options may include chemotherapy, stem cell transplantation, and targeted therapy.

Prognosis

The prognosis of smouldering myeloma varies greatly among individuals. Some people may live for many years without the disease progressing, while others may progress to active multiple myeloma within a few years.

Related Terms

External links

Medical encyclopedia article on Smouldering myeloma
Wikipedia's article - Smouldering myeloma

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Smouldering myeloma