Signet ring cell
Signet Ring Cell
Signet ring cell (/ˈsaɪ.nɪt rɪŋ sɛl/), also known as signet cell carcinoma, is a type of cancer cell that is characterized by its unique appearance under a microscope. The name "signet ring cell" is derived from the cell's resemblance to a signet ring, with a large vacuole and a peripheral nucleus.
Etymology
The term "signet ring cell" originates from the cell's resemblance to a signet ring. The word "signet" is derived from the Latin word "signum," meaning "sign," and the Old French word "signet," meaning "small seal." The term "cell" comes from the Latin word "cella," meaning "small room."
Definition
Signet ring cells are a type of epithelial cell that contain a large amount of mucin, a type of protein. This mucin pushes the cell's nucleus to one side, giving the cell the appearance of a signet ring when viewed under a microscope. Signet ring cells are most commonly associated with gastric cancer, but they can also be found in other types of cancer, such as colorectal cancer, breast cancer, and lung cancer.
Related Terms
- Mucin: A type of protein that is often found in high amounts in signet ring cells.
- Gastric cancer: A type of cancer that is often associated with signet ring cells.
- Epithelial cell: The type of cell that signet ring cells are classified as.
- Colorectal cancer: Another type of cancer that can contain signet ring cells.
- Breast cancer: A type of cancer that can also contain signet ring cells.
- Lung cancer: Another type of cancer that can contain signet ring cells.
External links
- Medical encyclopedia article on Signet ring cell
- Wikipedia's article - Signet ring cell
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