Serotonin-norepinephrine-dopamine reuptake inhibitor
Serotonin-Norepinephrine-Dopamine Reuptake Inhibitor (SNDRI), also known as a triple reuptake inhibitor (TRI), is a type of drug that acts as a combined reuptake inhibitor of the monoamine neurotransmitters serotonin, norepinephrine, and dopamine. It does this by concomitantly inhibiting the reuptake of these neurotransmitters via the serotonin transporter (SERT), norepinephrine transporter (NET), and dopamine transporter (DAT), respectively.
Pronunciation
Serotonin-Norepinephrine-Dopamine Reuptake Inhibitor: /sɛrəˈtoʊnɪn nɔːrɛpɪˈnɛfrɪn doʊpəˈmiːn riːˈʌptək ɪnˈhɪbɪtər/
Etymology
The term "Serotonin-Norepinephrine-Dopamine Reuptake Inhibitor" is derived from the names of the neurotransmitters it affects (serotonin, norepinephrine, and dopamine) and its function as a reuptake inhibitor.
Related Terms
- Serotonin: A neurotransmitter that helps regulate mood and social behavior, appetite and digestion, sleep, memory, and sexual desire and function.
- Norepinephrine: A neurotransmitter that is important for attentiveness, emotions, sleeping, dreaming, and learning.
- Dopamine: A neurotransmitter associated with pleasure and reward.
- Reuptake inhibitor: A type of drug that inhibits the reuptake of a neurotransmitter from the synapse into the presynaptic neuron, leading to an increase in the extracellular concentrations of the neurotransmitter.
See Also
- Selective serotonin reuptake inhibitor
- Serotonin-norepinephrine reuptake inhibitor
- Norepinephrine-dopamine reuptake inhibitor
This WikiMD.org article is a stub. You can help make it a full article.