Septal panniculitis

Septal Panniculitis

Septal Panniculitis (pronunciation: sep-tal pan-ick-yoo-lie-tis) is a medical condition characterized by inflammation of the septa within the subcutaneous fat. The term is derived from the Latin words 'septum', meaning 'partition', and 'panniculus', meaning 'little cloth', and the Greek word 'itis', meaning 'inflammation'.

Definition

Septal Panniculitis is a form of panniculitis that specifically affects the fibrous septa, the connective tissue strands that divide the subcutaneous fat into compartments. This condition can cause painful, tender nodules under the skin and may be associated with systemic symptoms such as fever and malaise.

Symptoms

The primary symptom of Septal Panniculitis is the presence of tender, erythematous nodules or plaques on the skin, typically on the lower legs. Other symptoms may include fever, malaise, and weight loss. In severe cases, ulceration and secondary infection may occur.

Causes

The exact cause of Septal Panniculitis is unknown, but it is thought to be related to an immune response to injury or inflammation in the subcutaneous fat. It can be associated with various systemic diseases, including lupus erythematosus, rheumatoid arthritis, and pancreatitis.

Diagnosis

Diagnosis of Septal Panniculitis is typically made based on the clinical presentation and histopathological examination of a skin biopsy. The biopsy will show inflammation and fibrosis in the septa of the subcutaneous fat.

Treatment

Treatment of Septal Panniculitis is aimed at reducing inflammation and managing any underlying systemic disease. This may involve the use of non-steroidal anti-inflammatory drugs (NSAIDs), corticosteroids, or other immunosuppressive agents.

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Septal panniculitis