Schaumann body
Schaumann Body
Schaumann body (pronunciation: /ʃaʊˈmɑːn ˈbɒdi/) is a type of inclusion body found in certain diseases, most notably sarcoidosis.
Etymology
The term "Schaumann body" is named after the Swedish pathologist Johan Erik Schaumann, who first described these structures in 1936.
Definition
Schaumann bodies are calcium and protein rich inclusions found in the granulomas associated with sarcoidosis. They are typically found within macrophages or giant cells and are considered a hallmark of the disease, although their exact role in the pathogenesis of sarcoidosis is not fully understood.
Related Terms
- Sarcoidosis: A disease involving abnormal collections of inflammatory cells that form lumps known as granulomas.
- Granuloma: A structure formed during inflammation that is found in many diseases.
- Macrophage: A type of white blood cell that engulfs and digests cellular debris, foreign substances, microbes, and cancer cells.
- Giant cell: A mass formed by the union of several distinct cells, often forming a granuloma.
- Inclusion body: A microscopic aggregation of substances, usually proteins, that is characteristic of certain diseases.
External links
- Medical encyclopedia article on Schaumann body
- Wikipedia's article - Schaumann body
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