Schaffer collateral

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Schaffer Collateral

Schaffer collateral (/ʃəˈfɛr kəˈlætərəl/), is a term used in neuroscience to describe the axons of the CA3 pyramidal cells in the hippocampus that connect to the CA1 region. The term is named after the neurologist Heinrich Schaffer, who first described this pathway.

Etymology

The term "Schaffer collateral" is derived from the name of the neurologist Heinrich Schaffer, who first identified and described this particular pathway in the brain. The term "collateral" is derived from the Latin word 'collaterale', which means "side by side". In this context, it refers to the axons that run alongside the main pathway in the hippocampus.

Function

The primary function of the Schaffer collaterals is to transmit signals from the CA3 region of the hippocampus to the CA1 region. This pathway plays a crucial role in the formation of memory and learning processes.

Related Terms

  • Axon: A long, slender projection of a nerve cell, or neuron, that typically conducts electrical impulses away from the neuron's cell body.
  • Hippocampus: A complex brain structure embedded deep into temporal lobe. It has a major role in learning and memory.
  • Neuron: A specialized cell transmitting nerve impulses; a nerve cell.
  • Pyramidal cell: A type of neuron in the cerebral cortex and the hippocampus in the brain.

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