SER-601
SER-601 is a drug currently under development by Serina Therapeutics for the treatment of inflammatory bowel disease (IBD). It is a polymer-bound form of budesonide, a corticosteroid used to treat a variety of conditions, including IBD.
Mechanism of Action
SER-601 works by releasing budesonide in the colon, where it reduces inflammation. This targeted delivery is designed to minimize systemic exposure to the drug, potentially reducing side effects.
Development and Clinical Trials
As of 2021, SER-601 is in Phase II clinical trials for the treatment of ulcerative colitis. The trial is a randomized, double-blind, placebo-controlled study evaluating the safety and efficacy of the drug in patients with moderate to severe ulcerative colitis.
Potential Advantages
SER-601 may offer several advantages over existing treatments for IBD. Its targeted delivery could reduce systemic exposure to corticosteroids, potentially reducing side effects. Additionally, the polymer-bound form of the drug may allow for a longer duration of action, potentially improving patient compliance.
See Also
References
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Contributors: Prab R. Tumpati, MD
