S100A10

S100A10

S100A10 (pronounced "S one hundred A ten"), also known as p11, is a protein that in humans is encoded by the S100A10 gene. It is a member of the S100 protein family, which is characterized by the presence of two EF-hand motifs.

Etymology

The name S100A10 is derived from the nature of the protein's solubility (S for soluble) in 100% saturated ammonium sulfate at neutral pH, and the A10 denotes its specific member number within the S100 protein family.

Function

S100A10 has a critical role in cellular processes such as endocytosis and exocytosis, and is involved in the regulation of plasminogen activation system which has significant implications in pathological processes including inflammation, wound healing, and cancer.

Clinical Significance

S100A10 has been found to be overexpressed in several types of cancer, including breast cancer, ovarian cancer, and pancreatic cancer. It is also associated with thrombosis and inflammation.

Related Terms

• S100 protein
• EF-hand motif
• Endocytosis
• Exocytosis
• Plasminogen
• Inflammation
• Wound healing
• Cancer
• Breast cancer
• Ovarian cancer
• Pancreatic cancer
• Thrombosis

External links

• Medical encyclopedia article on S100A10
• Wikipedia's article - S100A10

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