Ro07-9749
Ro07-9749 is a benzodiazepine derivative drug, which is a class of drugs used primarily for their muscle relaxant, anxiolytic, amnesic, sedative, and anticonvulsant properties. Ro07-9749 is a potent and selective agonist for the benzodiazepine receptor subtype, making it a useful research chemical in the study of the function of this receptor.
History
Ro07-9749 was first synthesized in the late 20th century as part of a series of benzodiazepine derivatives. The aim was to develop drugs with greater selectivity for different subtypes of the benzodiazepine receptor, in order to provide more targeted treatments with fewer side effects.
Pharmacology
Ro07-9749 is a potent and selective agonist for the benzodiazepine receptor subtype. This means it binds to this receptor and activates it, producing a biological response. In the case of Ro07-9749, this response is typically a calming or sedative effect.
Clinical Use
While Ro07-9749 has not been widely used in clinical practice, it has been a valuable tool in research. Its selectivity for the benzodiazepine receptor subtype has made it a useful chemical in the study of the function of this receptor, and in the development of new drugs that target this receptor.
Side Effects
As with all benzodiazepines, Ro07-9749 can have side effects. These can include drowsiness, confusion, and dependency with long-term use. However, because Ro07-9749 is not widely used in clinical practice, the full range of its potential side effects is not well known.
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Contributors: Prab R. Tumpati, MD