Rheumatoid neutrophilic dermatitis
| Rheumatoid neutrophilic dermatitis | |
|---|---|
| Synonyms | N/A |
| Pronounce | N/A |
| Specialty | N/A |
| Symptoms | Skin lesions, Rheumatoid arthritis |
| Complications | Infection, Scarring |
| Onset | Adulthood |
| Duration | Chronic |
| Types | N/A |
| Causes | Autoimmune disorder |
| Risks | Rheumatoid arthritis |
| Diagnosis | Clinical examination, Biopsy |
| Differential diagnosis | N/A |
| Prevention | N/A |
| Treatment | Corticosteroids, Immunosuppressants |
| Medication | N/A |
| Prognosis | Variable |
| Frequency | Rare |
| Deaths | N/A |
Rheumatoid neutrophilic dermatitis is a rare skin condition associated with rheumatoid arthritis. It is characterized by the presence of neutrophils in the dermis and is often seen in patients with active rheumatoid arthritis.
Presentation
Patients with rheumatoid neutrophilic dermatitis typically present with skin lesions that may appear as papules, nodules, or plaques. These lesions are often erythematous and may be pruritic. The condition is most commonly observed in adults with a history of rheumatoid arthritis.
Pathophysiology
The exact pathophysiology of rheumatoid neutrophilic dermatitis is not fully understood. It is believed to be an autoimmune disorder where the body's immune system mistakenly attacks its own skin tissues, leading to the accumulation of neutrophils in the dermis.
Diagnosis
Diagnosis of rheumatoid neutrophilic dermatitis is primarily based on clinical examination and biopsy of the affected skin. A histopathological examination typically reveals a dense infiltrate of neutrophils in the dermis.
Treatment
Treatment options for rheumatoid neutrophilic dermatitis include the use of corticosteroids and immunosuppressants to reduce inflammation and control the immune response. In some cases, treatment of the underlying rheumatoid arthritis may also lead to improvement in skin symptoms.
Prognosis
The prognosis for patients with rheumatoid neutrophilic dermatitis varies. While some patients may experience significant improvement with treatment, others may have persistent or recurrent skin lesions.
See also
References
External links
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Contributors: Prab R. Tumpati, MD