Rheumatoid neutrophilic dermatitis

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Rheumatoid neutrophilic dermatitis
Synonyms N/A
Pronounce N/A
Specialty N/A
Symptoms Skin lesions, Rheumatoid arthritis
Complications Infection, Scarring
Onset Adulthood
Duration Chronic
Types N/A
Causes Autoimmune disorder
Risks Rheumatoid arthritis
Diagnosis Clinical examination, Biopsy
Differential diagnosis N/A
Prevention N/A
Treatment Corticosteroids, Immunosuppressants
Medication N/A
Prognosis Variable
Frequency Rare
Deaths N/A


Rheumatoid neutrophilic dermatitis is a rare skin condition associated with rheumatoid arthritis. It is characterized by the presence of neutrophils in the dermis and is often seen in patients with active rheumatoid arthritis.

Presentation

Patients with rheumatoid neutrophilic dermatitis typically present with skin lesions that may appear as papules, nodules, or plaques. These lesions are often erythematous and may be pruritic. The condition is most commonly observed in adults with a history of rheumatoid arthritis.

Pathophysiology

The exact pathophysiology of rheumatoid neutrophilic dermatitis is not fully understood. It is believed to be an autoimmune disorder where the body's immune system mistakenly attacks its own skin tissues, leading to the accumulation of neutrophils in the dermis.

Diagnosis

Diagnosis of rheumatoid neutrophilic dermatitis is primarily based on clinical examination and biopsy of the affected skin. A histopathological examination typically reveals a dense infiltrate of neutrophils in the dermis.

Treatment

Treatment options for rheumatoid neutrophilic dermatitis include the use of corticosteroids and immunosuppressants to reduce inflammation and control the immune response. In some cases, treatment of the underlying rheumatoid arthritis may also lead to improvement in skin symptoms.

Prognosis

The prognosis for patients with rheumatoid neutrophilic dermatitis varies. While some patients may experience significant improvement with treatment, others may have persistent or recurrent skin lesions.

See also

References



External links

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Contributors: Prab R. Tumpati, MD