Reovirus

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Reovirus

Reovirus (/ˈriːoʊˌvaɪrəs/), short for respiratory enteric orphan virus, is a genus of double-stranded RNA viruses in the family Reoviridae.

Etymology

The term "Reovirus" is derived from Respiratory Enteric Orphan viruses. The term "orphan virus" was used because when these viruses were discovered, they were not associated with any known disease.

Structure

Reoviruses are non-enveloped viruses with an icosahedral capsid. The genome of the reovirus is segmented, consisting of 10-12 segments of double-stranded RNA.

Classification

Reoviruses are classified into the family Reoviridae, which is divided into two subfamilies: Sedoreovirinae and Spinareovirinae. The Reovirus genus belongs to the Spinareovirinae subfamily.

Pathogenesis

Reoviruses are typically benign pathogens in humans, but can cause severe disease in mice. They have been used extensively as a model organism in the study of viral pathogenesis.

Related Terms

See Also

External links

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