Renal osteodystrophy

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Renal Osteodystrophy

Renal osteodystrophy (/rɪˈnæl ˌɒstɪəʊˈdɪstrəfi/) is a bone disease that occurs when your kidneys fail to maintain the proper levels of calcium and phosphorus in your blood. It's a common problem in people with kidney disease and affects almost all patients at some stage of chronic kidney disease. The term "renal osteodystrophy" comes from the Greek words for "kidney", "bone", and "formation".

Causes

Renal osteodystrophy is caused by changes in the hormones that maintain calcium and phosphorus balance. The kidneys convert vitamin D from the skin and diet into its active form. When the kidneys are damaged, they can't make enough active vitamin D to keep the calcium and phosphorus in balance. This leads to bone loss and mineral imbalances, which can cause bone deformities and fractures.

Symptoms

Symptoms of renal osteodystrophy can vary widely, from bone pain and muscle weakness to fractures and deformities. In children, the disease can cause growth retardation and skeletal deformities, such as bowed legs or knock-knees.

Treatment

Treatment for renal osteodystrophy may include dialysis, medications to maintain calcium and phosphorus balance, and in some cases, parathyroidectomy (surgery to remove the parathyroid glands).

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