Phosphate binder

Phosphate binders are medications used to reduce the absorption of dietary phosphate; they are taken along with meals and snacks. They are frequently used in patients with chronic kidney disease (CKD) where they are used to treat hyperphosphatemia, a condition where there is an abnormally elevated level of phosphate in the blood.

Mechanism of Action

Phosphate binders work by binding to the phosphate in the gastrointestinal tract, thereby reducing its absorption into the body. This helps to maintain a balance of phosphate, which is important for bone health and the function of cells.

Types of Phosphate Binders

There are several types of phosphate binders, including:

• Calcium-based binders: These include calcium carbonate and calcium acetate.
• Non-calcium-based binders: These include sevelamer hydrochloride, lanthanum carbonate, and sucroferric oxyhydroxide.
• Iron-based binders: These include ferric citrate and sucroferric oxyhydroxide.

Side Effects

Like all medications, phosphate binders can have side effects. These can include:

• Nausea
• Vomiting
• Constipation
• Diarrhea

Patients should always discuss potential side effects with their healthcare provider before starting a new medication.

See Also

• Chronic kidney disease
• Hyperphosphatemia
• Phosphate

References

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