Radalbuvir

From WikiMD's medical encyclopedia

Radalbuvir is an experimental antiviral drug developed by Gilead Sciences for the treatment of hepatitis C. It is a nucleotide analogue inhibitor of the Hepatitis C virus NS5B polymerase.

History

Radalbuvir was first developed by Gilead Sciences, a biopharmaceutical company based in the United States. The drug is currently in the experimental stage and has not yet been approved for use in humans.

Mechanism of Action

Radalbuvir works by inhibiting the NS5B polymerase of the Hepatitis C virus, which is essential for viral replication. By blocking this enzyme, the drug prevents the virus from multiplying and spreading in the body.

Clinical Trials

Several clinical trials have been conducted to evaluate the safety and efficacy of Radalbuvir in patients with Hepatitis C. These trials have shown promising results, with many patients achieving a sustained virologic response after treatment with the drug.

Potential Side Effects

As with all drugs, Radalbuvir may cause side effects in some patients. These can include fatigue, headache, and nausea. However, these side effects are generally mild and manageable.

Future Developments

Research is ongoing to further evaluate the potential of Radalbuvir in the treatment of Hepatitis C. If successful, this drug could provide a new treatment option for patients with this chronic liver disease.

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Radalbuvir

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Contributors: Prab R. Tumpati, MD