Q10
Q10 (coenzyme)
Q10 (coenzyme) or Coenzyme Q10 (CoQ10) is a vitamin-like substance that is present in most eukaryotic cells, primarily in the mitochondria. It is a component of the electron transport chain and participates in aerobic cellular respiration, which generates energy in the form of adenosine triphosphate (ATP).
Structure and Function
Coenzyme Q10 is a benzoquinone, where Q refers to the quinone chemical group, and 10 refers to the number of isoprenyl chemical subunits in its tail. This fat-soluble substance, which resembles a vitamin, is present in most eukaryotic cells, primarily in the mitochondria. It is a component of the electron transport chain and participates in aerobic cellular respiration, generating energy in the form of ATP. Ninety-five percent of the human body’s energy is generated this way.
Dietary Sources
Coenzyme Q10 is naturally present in small amounts in a wide variety of foods but is particularly high in organ meats such as heart, liver, and kidney, as well as beef, soy oil, sardines, mackerel, and peanuts.
Health Benefits and Uses
Coenzyme Q10 has been used for treating or preventing a variety of health conditions, including heart disease, high blood pressure, and migraine headaches. It is also thought to boost energy and speed recovery from exercise.
Side Effects and Interactions
Coenzyme Q10 is generally well tolerated, even at high doses. However, some people may experience side effects such as stomach upset, loss of appetite, nausea, vomiting, and diarrhea. It can also cause allergic skin rashes in some people.
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Contributors: Prab R. Tumpati, MD