Pyridinoline
Pyridinoline
Pyridinoline (pronounced: py-ri-di-no-line) is a cross-linking compound that is found in collagen and elastin, two important structural proteins in the body. It is often used as a marker for bone and cartilage degradation in various medical conditions.
Etymology
The term "Pyridinoline" is derived from the chemical structure of the compound, which includes a pyridine ring, a type of aromatic heterocyclic compound.
Function
Pyridinoline cross-links are formed during the maturation of collagen and are responsible for the stability and strength of this protein. They are found in high concentrations in bone and cartilage, but can also be found in skin and other tissues. The presence of pyridinoline in urine is often used as a marker for bone and cartilage degradation, as it is released during the breakdown of these tissues.
Related Terms
- Collagen: A protein that provides structure to much of your body, including your skin, hair, nails, bones, and ligaments.
- Elastin: A highly elastic protein in connective tissue that allows many tissues in the body to resume their shape after stretching or contracting.
- Cross-link: A bond that links one polymer chain to another.
- Pyridine: A basic heterocyclic organic compound with the chemical formula C5H5N. It is structurally related to benzene, with one methine group (=CH−) replaced by a nitrogen atom.
External links
- Medical encyclopedia article on Pyridinoline
- Wikipedia's article - Pyridinoline
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