Protamine sulfate
Protamine Sulfate
Protamine sulfate (/proʊˈtæmiːn ˈsʌlfeɪt/) is a medication primarily used to reverse the effects of heparin, a type of anticoagulant. It is a highly positive charged peptide, obtained from the sperm of fish and certain other species.
Etymology
The term "protamine" is derived from the Greek words "protos" meaning first and "amine" due to its protein nature. The term "sulfate" refers to the salt form of the compound.
Pharmacology
Protamine sulfate works by binding to heparin to form a stable complex, thereby neutralizing its anticoagulant effect. It is often used during procedures such as cardiopulmonary bypass surgery to prevent excessive bleeding.
Related Terms
Side Effects
Like all medications, protamine sulfate can cause side effects. These may include allergic reactions, hypotension, and pulmonary hypertension.
See Also
References
- Medical references and scientific studies about Protamine Sulfate.
External links
- Medical encyclopedia article on Protamine sulfate
- Wikipedia's article - Protamine sulfate
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