Primary pulmonary coccidioidomycosis
Editor-In-Chief: Prab R Tumpati, MD
Obesity, Sleep & Internal medicine
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| Primary pulmonary coccidioidomycosis | |
|---|---|
| |
| Synonyms | Valley fever, San Joaquin Valley fever, Desert rheumatism |
| Pronounce | N/A |
| Specialty | N/A |
| Symptoms | Fever, cough, chest pain, fatigue, shortness of breath |
| Complications | Chronic pulmonary coccidioidomycosis, disseminated coccidioidomycosis |
| Onset | 1 to 3 weeks after exposure |
| Duration | Weeks to months |
| Types | N/A |
| Causes | Coccidioides immitis or Coccidioides posadasii |
| Risks | Immunocompromised, pregnancy, diabetes mellitus, African American or Filipino descent |
| Diagnosis | Serology, culture, PCR |
| Differential diagnosis | Tuberculosis, pneumonia, lung cancer |
| Prevention | Avoiding exposure in endemic areas |
| Treatment | Antifungal medications such as fluconazole or itraconazole |
| Medication | N/A |
| Prognosis | Generally good with treatment, but can be severe in immunocompromised individuals |
| Frequency | Endemic in the Southwestern United States, parts of Mexico, and Central America |
| Deaths | N/A |
Primary Pulmonary Coccidioidomycosis is a type of lung disease caused by the fungus Coccidioides. This disease is also known as Valley Fever, named after the San Joaquin Valley in California, where the fungus is endemic.
Etiology
Primary Pulmonary Coccidioidomycosis is caused by the inhalation of Coccidioides spores, which are found in the soil and dust of certain arid regions, particularly the southwestern United States, northern Mexico, and parts of Central America and South America. The two species of Coccidioides that cause the disease are Coccidioides immitis and Coccidioides posadasii.
Symptoms
The symptoms of Primary Pulmonary Coccidioidomycosis can range from mild to severe, and may include fever, cough, chest pain, fatigue, rash, and weight loss. In some cases, the disease can progress to disseminated coccidioidomycosis, which can affect other parts of the body and cause more serious symptoms.
Diagnosis
Diagnosis of Primary Pulmonary Coccidioidomycosis is typically made through laboratory testing, including serology and culture of respiratory specimens. Imaging studies, such as chest X-ray or CT scan, may also be used to identify abnormalities in the lungs.
Treatment
Treatment for Primary Pulmonary Coccidioidomycosis typically involves antifungal medication, such as fluconazole or itraconazole. In severe cases, hospitalization and more aggressive treatment may be required.
Prevention
Prevention strategies for Primary Pulmonary Coccidioidomycosis include avoiding activities that stir up dust in endemic areas, using respiratory protection when such activities cannot be avoided, and educating individuals about the disease and its symptoms.
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Contributors: Prab R. Tumpati, MD
