Phenampromide

Phenampromide

Phenampromide is a synthetic opioid that was developed in the late 1940s. It is a potent analgesic drug that is structurally related to methadone. Phenampromide has been used in the treatment of severe pain, although its use has been largely discontinued due to concerns about its potential for abuse and addiction.

History

Phenampromide was first synthesized in 1947 by the Hoffmann-La Roche company. It was initially marketed as a potent analgesic for the treatment of severe pain. However, it was soon discovered that the drug had a high potential for abuse and addiction, and its use was subsequently restricted.

Pharmacology

Phenampromide is a synthetic opioid, meaning it is a man-made drug that mimics the effects of naturally occurring opioids such as morphine. It works by binding to opioid receptors in the brain and spinal cord, which reduces the perception of pain.

The drug is metabolized in the liver and excreted in the urine. It has a half-life of approximately 2-3 hours.

Side Effects

Common side effects of phenampromide include nausea, vomiting, constipation, and drowsiness. More serious side effects can include respiratory depression, hypotension, and dependence.

Legal Status

Due to its high potential for abuse and addiction, phenampromide is classified as a Schedule II controlled substance in the United States. This means it is illegal to manufacture, distribute, or possess the drug without a valid prescription.

See Also

• Opioid
• Methadone
• Opioid receptor
• Schedule II controlled substance

References

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