Pentalogy of cantrell

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Pentalogy of Cantrell (pronounced: pen-tal-uh-jee of kan-trell) is a rare congenital disorder characterized by a combination of five distinct anomalies. These include:

  1. Defect of the supraumbilical abdominal wall
  2. Deficiency of the anterior diaphragm
  3. Defect in the diaphragmatic pericardium
  4. Congenital intracardiac abnormalities
  5. Defect in the lower sternum

The term "Pentalogy of Cantrell" was first coined in 1958 by American pathologist James Cantrell, hence the etymology of the term.

Etiology

The exact cause of Pentalogy of Cantrell is unknown. However, it is believed to be due to a disruption in the embryonic development process during the early stages of pregnancy.

Symptoms

The symptoms of Pentalogy of Cantrell can vary greatly depending on the severity of the condition. They may include:

Diagnosis

Diagnosis of Pentalogy of Cantrell is typically made through a combination of physical examination, imaging studies such as ultrasound and MRI, and genetic testing.

Treatment

Treatment for Pentalogy of Cantrell is typically surgical and aims to correct the anatomical defects. The exact type of surgery will depend on the specific defects present.

Prognosis

The prognosis for individuals with Pentalogy of Cantrell can vary greatly depending on the severity of the condition and the specific defects present. Some individuals may lead relatively normal lives with appropriate treatment, while others may have significant health challenges.

See Also

External links

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