Pemphigus erythematosus

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Pemphigus erythematosus
Synonyms	Senear–Usher syndrome
Pronounce	N/A
Specialty	Dermatology
Symptoms	Blisters, erosions, crusts
Complications	Infection, scarring
Onset	Middle age
Duration	Chronic
Types	N/A
Causes	Autoimmune disease
Risks	Genetic predisposition, environmental factors
Diagnosis	Skin biopsy, direct immunofluorescence
Differential diagnosis	Lupus erythematosus, pemphigus vulgaris
Prevention	N/A
Treatment	Corticosteroids, immunosuppressive drugs
Medication	N/A
Prognosis	Variable, can be controlled with treatment
Frequency	Rare
Deaths	N/A

Pemphigus Erythematosus is a rare, chronic, autoimmune skin disorder that is a variant of Pemphigus Foliaceus. It is also known as Senear-Usher syndrome.

Symptoms

The symptoms of Pemphigus Erythematosus include skin lesions that are scaly and crusted. These lesions are often found on the face, scalp, chest, and back. The lesions may also appear in the mouth, but this is less common. The skin around the lesions may be red and inflamed.

Causes

Pemphigus Erythematosus is caused by the body's immune system attacking the cells in the top layer of the skin (the epidermis) and the mucous membranes. The exact reason why this happens is not known, but it is thought to be related to genetic factors and possibly triggered by environmental factors.

Diagnosis

The diagnosis of Pemphigus Erythematosus is usually made by a dermatologist based on the appearance of the skin lesions. A skin biopsy may be taken to confirm the diagnosis. Blood tests may also be done to check for the presence of certain antibodies that are often found in people with this condition.

Treatment

The treatment for Pemphigus Erythematosus usually involves the use of medications to suppress the immune system and reduce inflammation. These may include corticosteroids, immunosuppressant drugs, and antibiotics to treat any secondary infections. In severe cases, hospitalization may be required.

Prognosis

The prognosis for Pemphigus Erythematosus is generally good with treatment. Most people with this condition are able to lead normal lives. However, it is a chronic condition and symptoms may recur from time to time.

Pemphigus_erythematosus gallery

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  Pemphigus erythematosus
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  Desmosome cell junction
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  Rituximab (MabTas)

See also

• Pemphigus
• Pemphigus Foliaceus
• Autoimmune disease
• Dermatology