Pemoline

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Pemoline

Pemoline (pronounced: /pɛˈmoʊliːn/) is a stimulant drug of the 4-oxazolidinone class. It was first synthesized in 1913 but its activity was not discovered until the 1930s. Under the names Betanamin, Cylert, Tradon, and Ceractiv it was used as a medication to treat attention-deficit hyperactivity disorder (ADHD) and narcolepsy.

Etymology

The term "Pemoline" is derived from its chemical name, 2-amino-5-phenyl-1,3-oxazol-4-one. The name is a combination of the words phenyl, methyl, and oxazolone, which describe its chemical structure.

Usage

Pemoline is used primarily to treat ADHD and narcolepsy. It works by increasing the amount of certain chemicals in the brain that help with attention and behavior. However, due to its potential for liver toxicity, it is rarely used today.

Side Effects

Common side effects of Pemoline include insomnia, increased heart rate, and irritability. In rare cases, it can cause severe liver damage, leading to its withdrawal from the market in several countries.

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