Pallidotomy
Pallidotomy is a neurosurgical procedure that involves the precise destruction of a small part of the globus pallidus, a component of the basal ganglia in the brain. This procedure is primarily used to treat the symptoms of Parkinson's disease and other movement disorders.
History[edit]
Pallidotomy was first developed in the mid-20th century as a treatment for Parkinson's disease. The procedure gained popularity in the 1990s with the advent of modern imaging techniques that allowed for more precise targeting of the globus pallidus.
Indications[edit]
Pallidotomy is indicated for patients with Parkinson's disease who experience severe motor symptoms that are not adequately controlled by medication. These symptoms may include tremor, rigidity, and bradykinesia.
Procedure[edit]
The procedure is typically performed under local anesthesia with the patient awake, allowing for real-time feedback during surgery. A small hole is drilled in the skull, and a probe is inserted into the globus pallidus. The target area is then lesioned using heat generated by radiofrequency energy.
Mechanism of Action[edit]
The globus pallidus is part of the basal ganglia, which play a crucial role in the regulation of voluntary movement. In Parkinson's disease, the normal functioning of the basal ganglia is disrupted, leading to the characteristic motor symptoms. By lesioning a part of the globus pallidus, pallidotomy aims to restore balance in the basal ganglia circuitry, thereby alleviating symptoms.
Outcomes[edit]
Pallidotomy can lead to significant improvement in motor symptoms for many patients. However, the procedure is not without risks, and potential complications include speech disorders, cognitive impairment, and hemiparesis.
Alternatives[edit]
Other surgical options for treating Parkinson's disease include deep brain stimulation (DBS), which involves the implantation of electrodes in the brain to modulate neural activity. Unlike pallidotomy, DBS is reversible and adjustable.
Related pages[edit]
Ad. Transform your health with W8MD Weight Loss, Sleep & MedSpa
Tired of being overweight?
Special offer:
Budget GLP-1 weight loss medications
- Semaglutide starting from $29.99/week and up with insurance for visit of $59.99 and up per week self pay.
- Tirzepatide starting from $45.00/week and up (dose dependent) or $69.99/week and up self pay
✔ Same-week appointments, evenings & weekends
Learn more:
- GLP-1 weight loss clinic NYC
- W8MD's NYC medical weight loss
- W8MD Philadelphia GLP-1 shots
- Philadelphia GLP-1 injections
- Affordable GLP-1 shots NYC
- Budget GLP-1 shots
|
WikiMD Medical Encyclopedia |
Medical Disclaimer: WikiMD is for informational purposes only and is not a substitute for professional medical advice. Content may be inaccurate or outdated and should not be used for diagnosis or treatment. Always consult your healthcare provider for medical decisions. Verify information with trusted sources such as CDC.gov and NIH.gov. By using this site, you agree that WikiMD is not liable for any outcomes related to its content. See full disclaimer.
Credits:Most images are courtesy of Wikimedia commons, and templates, categories Wikipedia, licensed under CC BY SA or similar.
Translate this page: - East Asian
中文,
日本,
한국어,
South Asian
हिन्दी,
தமிழ்,
తెలుగు,
Urdu,
ಕನ್ನಡ,
Southeast Asian
Indonesian,
Vietnamese,
Thai,
မြန်မာဘာသာ,
বাংলা
European
español,
Deutsch,
français,
Greek,
português do Brasil,
polski,
română,
русский,
Nederlands,
norsk,
svenska,
suomi,
Italian
Middle Eastern & African
عربى,
Turkish,
Persian,
Hebrew,
Afrikaans,
isiZulu,
Kiswahili,
Other
Bulgarian,
Hungarian,
Czech,
Swedish,
മലയാളം,
मराठी,
ਪੰਜਾਬੀ,
ગુજરાતી,
Portuguese,
Ukrainian
