Overgrowth
Overgrowth refers to the excessive growth of the body or a part of the body. It is often associated with a number of genetic disorders and syndromes, and can affect any part of the body. Overgrowth can be localized, affecting just one part of the body, or generalized, affecting the entire body.
Causes
Overgrowth can be caused by a number of different factors, including genetic mutations, hormonal imbalances, and certain medical conditions. Some of the most common causes include:
- Beckwith-Wiedemann syndrome: This is a genetic disorder that can cause overgrowth of the body or parts of the body. It is often associated with an increased risk of cancer.
- Proteus syndrome: This is a rare condition that can cause overgrowth of the skin, bones, and other tissues. It is often associated with a number of other health problems, including intellectual disability and seizures.
- Sotos syndrome: This is a genetic disorder that can cause overgrowth during the first few years of life. It is often associated with learning disabilities and behavioral problems.
Symptoms
The symptoms of overgrowth can vary widely depending on the underlying cause. Some of the most common symptoms include:
- Abnormal growth: This is the most common symptom of overgrowth. It can affect any part of the body, and can range from mild to severe.
- Physical deformities: In some cases, overgrowth can cause physical deformities. This can include things like macrocephaly (an abnormally large head), gigantism (excessive height), and acromegaly (enlargement of the hands and feet).
- Health problems: Overgrowth can also cause a number of health problems. This can include things like heart disease, diabetes, and cancer.
Treatment
Treatment for overgrowth depends on the underlying cause. In some cases, treatment may involve surgery to remove or reduce the size of the overgrown tissue. In other cases, treatment may involve medication to manage the symptoms or underlying condition.
See also
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Contributors: Prab R. Tumpati, MD