Oncocyte

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Oncocyte

Oncocyte (pronounced: on-co-site) is a term used in medicine and pathology to describe a large cell with abundant cytoplasm and small, often eccentrically located nucleus. These cells are typically found in certain types of tumors and are characterized by their excessive number of mitochondria. The term "oncocyte" is derived from the Greek words "onkos" meaning mass or bulk, and "kytos" meaning cell.

Etymology

The term "oncocyte" is derived from the Greek words "onkos" meaning mass or bulk, and "kytos" meaning cell. It was first used in the medical literature in the mid-20th century to describe cells with an unusually large amount of cytoplasm and a small, often eccentrically located nucleus.

Related Terms

  • Oncocytoma: A tumor composed predominantly of oncocytes. It is usually benign and occurs most commonly in the kidney, salivary glands, and thyroid gland.
  • Oncocytic metaplasia: A condition in which normal cells are replaced by oncocytes. This is often seen in chronic inflammation and aging.
  • Oncocytic carcinoma: A malignant tumor composed of oncocytes. This is a rare type of cancer that can occur in various organs, including the thyroid and salivary glands.
  • Oncocytic adenoma: A benign tumor composed of oncocytes. This type of tumor is most commonly found in the salivary glands.

See Also

External links

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