Oculomucocutaneous syndrome

Oculomucocutaneous syndrome
Synonyms	Stevens-Johnson syndrome, Lyell's syndrome
Pronounce	N/A
Specialty	N/A
Symptoms	Conjunctivitis, keratitis, skin rash, oral ulcers
Complications	Blindness, scarring, infection
Onset	Sudden
Duration	Variable
Types	N/A
Causes	Adverse drug reaction, infection
Risks	Medication use, viral infections
Diagnosis	Clinical examination, biopsy
Differential diagnosis	Pemphigus vulgaris, toxic epidermal necrolysis
Prevention	N/A
Treatment	Corticosteroids, supportive care
Medication	Antibiotics, analgesics
Prognosis	Variable, can be severe
Frequency	Rare
Deaths	N/A

Oculomucocutaneous syndrome is a rare medical condition that affects the eyes, mucous membranes, and skin. It is often associated with the use of certain medications, particularly the drug practolol, a beta-blocker used to treat high blood pressure and heart conditions.

Symptoms

The symptoms of oculomucocutaneous syndrome can vary widely, but often include:

• Dry eyes
• Conjunctivitis (inflammation of the eye)
• Blepharitis (inflammation of the eyelids)
• Skin rash
• Mucous membrane abnormalities

Causes

Oculomucocutaneous syndrome is most commonly associated with the use of the drug practolol. However, it can also occur as a result of other medications or underlying health conditions.

Diagnosis

Diagnosis of oculomucocutaneous syndrome is typically based on the presence of characteristic symptoms and a history of exposure to certain medications. Additional tests, such as a skin biopsy, may be performed to confirm the diagnosis.

Treatment

Treatment for oculomucocutaneous syndrome typically involves discontinuing the medication that is causing the condition. Additional treatments, such as topical steroids or artificial tears, may be used to manage symptoms.

See also

• Practolol
• Beta-blocker
• Mucous membrane

References

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