Nutriepigenomics

Nutriepigenomics (pronunciation: /nuː.triː.epiː.genˈoʊ.mɪks/) is a scientific discipline that studies the effects of nutrition and dietary components on the epigenome. The term is derived from the words "nutrition", "epigenetics", and "genomics".

Etymology

The term "Nutriepigenomics" is a portmanteau of three words: "Nutri" from Nutrition, "epi" from Epigenetics, and "genomics" from Genomics. Nutrition refers to the intake of food, considered in relation to the body’s dietary needs. Epigenetics is the study of changes in organisms caused by modification of gene expression rather than alteration of the genetic code itself. Genomics is a discipline in genetics that applies recombinant DNA, DNA sequencing methods, and bioinformatics to sequence, assemble, and analyze the function and structure of genomes.

Overview

Nutriepigenomics is an emerging field in nutritional science that seeks to understand how diet influences gene expression through epigenetic mechanisms. These mechanisms include DNA methylation, histone modification, and non-coding RNA molecules. The field is based on the understanding that while our genetic code (our genome) is fixed, the way our genes are expressed can be altered by environmental factors, including diet.

Related Terms

Epigenetics: The study of changes in organisms caused by modification of gene expression rather than alteration of the genetic code itself.
Genomics: A discipline in genetics that applies recombinant DNA, DNA sequencing methods, and bioinformatics to sequence, assemble, and analyze the function and structure of genomes.
Nutrigenomics: The scientific study of the interaction of nutrition and genes, especially with regard to the prevention or treatment of disease.
DNA methylation: A biological process by which methyl groups are added to the DNA molecule.
Histone modification: A covalent post-translational modification to histone proteins which includes methylation, phosphorylation, acetylation, ubiquitylation, and sumoylation.
Non-coding RNA: A functional RNA molecule that is not translated into a protein.

External links

Medical encyclopedia article on Nutriepigenomics
Wikipedia's article - Nutriepigenomics

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Nutriepigenomics