Norethindrone acetate

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Norethindrone Acetate

Norethindrone Acetate (pronunciation: nor-ETH-in-drone AS-e-tate) is a synthetic progestational hormone with actions similar to those of progesterone but functioning as a more potent inhibitor of ovulation. It has weak estrogenic and androgenic properties. The acetate is administered orally.

Etymology

The term "Norethindrone" is derived from the chemical name 17α-ethynyl-19-nortestosterone. The "Acetate" part refers to the acetic acid ester that is formed during the process of esterification.

Pharmacology

Norethindrone Acetate is used for the prevention of pregnancy in women who elect to use this product as a method of contraception. It is also used for the treatment of secondary amenorrhea, endometriosis, and abnormal uterine bleeding due to hormonal imbalance in the absence of organic pathology, such as fibroids or uterine cancer.

Related Terms

  • Progesterone: A hormone that prepares the uterus for the reception and development of the fertilized ovum.
  • Ovulation: The release of an egg from one of the ovaries.
  • Estrogen: A group of hormones that promote the development and maintenance of female characteristics of the body.
  • Androgen: Any natural or synthetic compound, usually a steroid hormone, that stimulates or controls the development and maintenance of male characteristics.
  • Amenorrhea: The absence of menstruation.
  • Endometriosis: A disorder in which tissue similar to the tissue that forms the lining of the uterus grows outside of the uterine cavity.
  • Uterine bleeding: Abnormal bleeding from the blood vessels of the uterus.

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