Pleomorphic T-cell lymphoma

Pleomorphic T-cell lymphoma
Synonyms
Pronounce	N/A
Specialty	Hematology, Oncology
Symptoms	Lymphadenopathy, fever, weight loss, night sweats
Complications	N/A
Onset
Duration
Types
Causes	Unknown
Risks
Diagnosis	Biopsy, immunophenotyping, genetic testing
Differential diagnosis	Other types of T-cell lymphoma, B-cell lymphoma
Prevention
Treatment	Chemotherapy, radiation therapy, stem cell transplant
Medication
Prognosis	Variable, depends on stage and response to treatment
Frequency	Rare
Deaths	N/A

Pleomorphic T-cell lymphoma is a type of non-Hodgkin lymphoma that affects the T cells in the immune system. It is characterized by a diverse range of cell shapes and sizes, hence the term "pleomorphic". This lymphoma is considered a subtype of peripheral T-cell lymphoma, which is a group of rare and aggressive lymphomas that develop from mature T cells.

Symptoms

The symptoms of pleomorphic T-cell lymphoma can vary widely, but may include fever, night sweats, weight loss, and fatigue. Swollen lymph nodes are also a common symptom.

Diagnosis

Diagnosis of pleomorphic T-cell lymphoma typically involves a biopsy of an affected lymph node or other tissue. The biopsy sample is then examined under a microscope to identify the presence of abnormal T cells. Other tests, such as blood tests, imaging tests, and a bone marrow biopsy, may also be used to help confirm the diagnosis and determine the extent of the disease.

Treatment

Treatment for pleomorphic T-cell lymphoma often involves chemotherapy, with or without radiation therapy. In some cases, a stem cell transplant may be considered. The choice of treatment depends on a number of factors, including the patient's overall health, the stage of the disease, and the patient's personal preferences.

Prognosis

The prognosis for pleomorphic T-cell lymphoma can vary widely, depending on factors such as the patient's age, overall health, and the stage of the disease at diagnosis. In general, however, this type of lymphoma is considered to be aggressive and difficult to treat.

See also

• Non-Hodgkin lymphoma
• Peripheral T-cell lymphoma
• T cells
• Immune system

This article is a medical stub. You can help WikiMD by expanding it!
Most recent articles Ongoing trials	Wikipedia