Nomegestrol acetate/estradiol

Nomegestrol acetate/estradiol is a combined estrogen and progestogen medication which is used in menopausal hormone therapy and as a birth control method. It contains nomegestrol acetate, a progestogen, and estradiol, an estrogen. The medication is taken by mouth.

Medical uses

Nomegestrol acetate/estradiol is used in menopausal hormone therapy for the treatment of menopausal symptoms such as hot flashes and vaginal dryness. It is also used as a method of birth control.

Side effects

Possible side effects of nomegestrol acetate/estradiol include menstrual irregularities, breast tenderness, and nausea. In rare cases, it may increase the risk of blood clots, stroke, and certain types of cancer.

Pharmacology

Nomegestrol acetate is a progestogen, or a synthetic progestogen, which has effects similar to those of natural progesterone. Estradiol is a naturally occurring estrogen, or a form of estrogen that is identical to the estrogen produced by the human body.

History

Nomegestrol acetate/estradiol was first introduced for medical use in France in 1986. It is now available in many countries worldwide.

Society and culture

Nomegestrol acetate/estradiol is marketed under a number of brand names including Zoely, Naemis, and Merigest.

See also

• List of combined sex-hormonal preparations
• List of contraceptives
• List of sex hormones

Nomegestrol_acetate/estradiol

• 
  Nomegestrol acetate chemical structure
• 
  Estradiol chemical structure
• 
  Diagram of a synaptonemal complex