Nodular sclerosis
Nodular Sclerosis (pronunciation: noh-duh-lar skle-roh-sis) is a subtype of Hodgkin's lymphoma, a type of cancer that originates from a specific kind of white blood cells known as lymphocytes.
Etymology
The term "Nodular Sclerosis" is derived from two words. "Nodular" comes from the Latin word "nodulus" meaning "small knot", referring to the characteristic nodular growth pattern of the lymphoma. "Sclerosis" is derived from the Greek word "sklerosis" meaning "hardening", referring to the hard, fibrous tissue that is often found in these tumors.
Definition
Nodular Sclerosis is characterized by the presence of large, abnormal cells known as Reed-Sternberg cells in the lymph nodes. These cells are typically surrounded by bands of fibrous tissue, which can cause the lymph nodes to become hard and form nodules.
Symptoms
Common symptoms of Nodular Sclerosis include painless swelling of the lymph nodes in the neck, armpits, or groin, unexplained weight loss, night sweats, and fatigue.
Diagnosis
Diagnosis of Nodular Sclerosis typically involves a physical examination, blood tests, imaging tests such as a CT scan or PET scan, and a biopsy of the affected lymph node.
Treatment
Treatment for Nodular Sclerosis usually involves chemotherapy, radiation therapy, or a combination of both. In some cases, a stem cell transplant may be considered.
Related Terms
- Hodgkin's lymphoma
- Lymphocytes
- Reed-Sternberg cells
- CT scan
- PET scan
- Biopsy
- Chemotherapy
- Radiation therapy
- Stem cell transplant
External links
- Medical encyclopedia article on Nodular sclerosis
- Wikipedia's article - Nodular sclerosis
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