Histiocyte
(Redirected from Histiocytes)
Histiocyte is a type of immune cell that is part of the mononuclear phagocyte system. These cells are derived from monocytes, a type of white blood cell, and are located in tissues throughout the body. Histiocytes play a crucial role in the immune response by helping to fight off infections and diseases.
Function
Histiocytes are involved in the body's immune response. They help to fight off infections and diseases by engulfing and digesting foreign substances, such as bacteria and viruses. This process is known as phagocytosis. In addition to their role in the immune response, histiocytes also play a role in tissue repair and regeneration.
Types of Histiocytes
There are several types of histiocytes, including:
- Macrophages: These are the most common type of histiocyte. They are found in tissues throughout the body and are involved in both the immune response and tissue repair.
 
- Dendritic cells: These histiocytes are found in the skin and mucous membranes. They are involved in the immune response by presenting antigens to T cells.
 
- Langerhans cells: These histiocytes are found in the skin and are involved in the immune response by presenting antigens to T cells.
 
Diseases and Disorders
There are several diseases and disorders associated with histiocytes, including:
- Histiocytosis: This is a group of diseases characterized by an overproduction of histiocytes. This can lead to tissue damage and organ dysfunction.
 
- Langerhans cell histiocytosis: This is a rare disease characterized by an overproduction of Langerhans cells.
 
- Hemophagocytic lymphohistiocytosis: This is a rare and potentially fatal disease characterized by an overactive immune response.
 
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Contributors: Prab R. Tumpati, MD