Nitroxinil
Nitroxinil
Nitroxinil (pronounced as ni-trox-i-nil) is a chemical compound used primarily as an anthelmintic agent in veterinary medicine. It is particularly effective against liver fluke infections in sheep and cattle.
Etymology
The term "Nitroxinil" is derived from its chemical structure, which includes a nitro group (NO2) and a hydroxyl group (OH). The "-inil" suffix is common in the names of chemical compounds.
Usage
Nitroxinil is used in the treatment of Fasciolosis, a parasitic infection caused by the liver fluke, Fasciola hepatica. It is also effective against other types of flukes, such as Fasciola gigantica and Dicrocoelium dendriticum. Nitroxinil is administered by subcutaneous injection and is typically used when other treatments, such as Triclabendazole, have failed.
Mechanism of Action
Nitroxinil works by inhibiting the enzyme fumarate reductase, which is essential for the survival of the fluke. This causes the parasite to starve and eventually die.
Side Effects
Possible side effects of Nitroxinil include local tissue reactions at the injection site, which may result in temporary discomfort for the animal. In rare cases, allergic reactions may occur.
Related Terms
- Anthelmintic: A type of drug used to expel parasitic worms from the body.
- Fasciolosis: A parasitic infection caused by the liver fluke.
- Fumarate reductase: An enzyme that is essential for the survival of certain parasites.
- Triclabendazole: Another drug used in the treatment of liver fluke infections.
External links
- Medical encyclopedia article on Nitroxinil
- Wikipedia's article - Nitroxinil
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