Nezelof syndrome

Nezelof Syndrome

Nezelof Syndrome (pronunciation: neh-zuh-lof sin-drohm) is a rare immunodeficiency disorder characterized by a decrease in the number of T cells or lymphocytes, which are crucial components of the immune system. The syndrome is named after the French pediatrician and pathologist, Henri Nezelof, who first described the condition in 1964.

Etymology

The term "Nezelof Syndrome" is derived from the name of its discoverer, Dr. Henri Nezelof. The word "syndrome" comes from the Greek "syndromē," which means "concurrence of symptoms," or "running together."

Symptoms

The symptoms of Nezelof Syndrome can vary greatly among affected individuals. However, common symptoms include recurrent infections, growth retardation, and diarrhea. Due to the decreased number of T cells, individuals with Nezelof Syndrome are more susceptible to infections, particularly those caused by bacteria, viruses, and fungi.

Diagnosis

Diagnosis of Nezelof Syndrome is typically made based on a thorough clinical evaluation, a detailed patient history, and specialized tests such as immunologic studies and genetic testing. These tests can help identify the decrease in T cells, which is characteristic of the syndrome.

Treatment

Treatment for Nezelof Syndrome is focused on managing the symptoms and preventing complications. This may include antibiotic therapy for infections, immunoglobulin therapy to boost the immune system, and in severe cases, a bone marrow transplant may be considered.

Related Terms

External links

Medical encyclopedia article on Nezelof syndrome
Wikipedia's article - Nezelof syndrome

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