Mycobacterium malmoense
Mycobacterium malmoense is a species of bacteria belonging to the genus Mycobacterium. It was first isolated in Malmo, Sweden in 1954, hence its name. It is a non-tuberculous mycobacterium (NTM) and is considered a slow-growing mycobacterium.
Characteristics
Mycobacterium malmoense is a slow-growing, acid-fast bacterium. It is non-motile and does not form spores. The bacterium is characterized by its ability to grow at both room temperature and body temperature, and it can survive in a wide range of environments.
Pathogenesis
Mycobacterium malmoense is an opportunistic pathogen, meaning it typically causes disease in individuals with weakened immune systems. It can cause a variety of diseases, including pulmonary disease, lymphadenitis, and skin disease. Pulmonary disease is the most common manifestation of infection with Mycobacterium malmoense.
Diagnosis
Diagnosis of Mycobacterium malmoense infection is typically made through microbiological culture of a patient's sputum or tissue sample. The bacterium can be identified based on its characteristic growth pattern and appearance under a microscope.
Treatment
Treatment of Mycobacterium malmoense infection typically involves a combination of antibiotics, including rifampicin, ethambutol, and macrolides. Treatment duration can vary, but is typically long-term due to the slow-growing nature of the bacterium.
Epidemiology
Mycobacterium malmoense is most commonly found in Northern Europe, particularly in the United Kingdom, Sweden, and Denmark. However, it has been isolated in other parts of the world as well.
See also
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Contributors: Prab R. Tumpati, MD