Oligoastrocytoma

Editor-In-Chief: Prab R Tumpati, MD
Obesity, Sleep & Internal medicine
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Oligoastrocytoma
Synonyms	Mixed glioma
Pronounce	N/A
Specialty	N/A
Symptoms	Seizures, headache, neurological deficit
Complications	N/A
Onset	Typically in adulthood
Duration	Variable
Types	N/A
Causes	Genetic mutations
Risks	Family history, radiation exposure
Diagnosis	MRI, CT scan, biopsy
Differential diagnosis	Oligodendroglioma, astrocytoma, glioblastoma
Prevention	N/A
Treatment	Surgery, radiation therapy, chemotherapy
Medication	N/A
Prognosis	Variable, depends on grade and treatment response
Frequency	Rare
Deaths	N/A

MRI of Oligoastrocytoma

PiB PET Images in Alzheimer's Disease

Oligoastrocytoma is a type of brain tumor that originates from glial cells, the supportive cells of the brain. It is a mixed glioma that contains both astrocytoma and oligodendroglioma components. Oligoastrocytomas are rare, accounting for approximately 2.3% of all primary brain tumors.

Classification

Oligoastrocytomas are classified by the World Health Organization (WHO) into two grades: grade II (low-grade) and grade III (anaplastic). The grade is determined by the presence of certain cellular characteristics, such as mitosis, necrosis, and vascular proliferation.

Symptoms

The symptoms of oligoastrocytoma can vary depending on the location and size of the tumor. Common symptoms include headache, seizure, nausea, vomiting, and neurological deficits such as weakness or numbness.

Diagnosis

Diagnosis of oligoastrocytoma typically involves neuroimaging techniques such as magnetic resonance imaging (MRI) and computed tomography (CT) scans. A definitive diagnosis is made by biopsy, where a sample of the tumor is examined under a microscope.

Treatment

Treatment for oligoastrocytoma often involves a combination of surgery, radiation therapy, and chemotherapy. The choice of treatment depends on the grade of the tumor, the patient's overall health, and the location and size of the tumor.

Prognosis

The prognosis for patients with oligoastrocytoma varies depending on the grade of the tumor, the patient's age and overall health, and the extent of tumor removal. The median survival time for patients with grade II oligoastrocytoma is 6-8 years, while for grade III oligoastrocytoma it is 3-5 years.

See also

• Glioma
• Astrocytoma
• Oligodendroglioma

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