Michelin tire baby syndrome

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Michelin Tire Baby Syndrome

Michelin Tire Baby Syndrome (pronunciation: mi-she-lan tyre bay-bee sin-drome), also known as Lipomatous Hypertrophy or Circumferential Skin Folds, is a rare genetic disorder characterized by multiple, symmetric, circular skin folds. The name is derived from the Michelin Tire mascot, as the physical appearance of individuals with this condition is reminiscent of the mascot's multiple tire-like rolls.

Etymology

The term "Michelin Tire Baby Syndrome" was coined in 1967 by a French pediatrician, Jacques Léauté-Labrèze, who noticed the similarity between the physical appearance of affected individuals and the Michelin Tire Company's mascot, Bibendum, who is commonly known as the Michelin Man. The term "Michelin" is a reference to the Michelin Tire Company, and the term "baby" refers to the fact that the condition is usually noticeable at birth or early infancy.

Symptoms

The primary symptom of Michelin Tire Baby Syndrome is the presence of multiple, symmetric, circular skin folds, which are most commonly present around the limbs and trunk. Other symptoms may include developmental delay, intellectual disability, and musculoskeletal abnormalities. Some individuals may also have lipomas, which are benign fatty tumors.

Causes

Michelin Tire Baby Syndrome is a genetic disorder, which means it is caused by changes (mutations) in one or more genes. However, the exact genetic cause of the condition is not yet known. It is thought to be inherited in an autosomal dominant manner, which means one copy of the altered gene in each cell is sufficient to cause the disorder.

Diagnosis

Diagnosis of Michelin Tire Baby Syndrome is based on the characteristic physical features. Genetic testing may be used to confirm the diagnosis and to identify the specific gene mutation.

Treatment

Treatment for Michelin Tire Baby Syndrome is symptomatic and supportive. This may include physical therapy to improve mobility and surgical removal of the skin folds if they cause discomfort or restrict movement.

See Also

External links

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