Lymphocytopenia
| Lymphocytopenia | |
|---|---|
| Synonyms | Lymphopenia |
| Pronounce | N/A |
| Specialty | N/A |
| Symptoms | Fatigue, infections, fever, malaise |
| Complications | Increased risk of infection |
| Onset | Can be acute or chronic |
| Duration | Varies depending on cause |
| Types | N/A |
| Causes | Autoimmune disease, HIV/AIDS, malnutrition, chemotherapy, radiation therapy, bone marrow disorders |
| Risks | Immunodeficiency, autoimmune diseases |
| Diagnosis | Complete blood count, flow cytometry |
| Differential diagnosis | Aplastic anemia, HIV/AIDS, leukemia, sepsis |
| Prevention | N/A |
| Treatment | Address underlying cause, immunoglobulin therapy, antibiotics for infections |
| Medication | N/A |
| Prognosis | Depends on underlying cause |
| Frequency | Varies |
| Deaths | N/A |
Lymphocytopenia is a condition characterized by abnormally low levels of lymphocytes in the blood. Lymphocytes are a type of white blood cell that play a crucial role in the immune system, helping the body fight off infections and diseases.
Causes
Lymphocytopenia can be caused by a variety of factors, including:
- Certain infections, such as HIV/AIDS, tuberculosis, and hepatitis
- Autoimmune disorders, such as lupus and rheumatoid arthritis
- Certain types of cancer, including leukemia and lymphoma
- Chemotherapy and radiation therapy, which can damage the bone marrow and affect lymphocyte production
- Certain medications, such as corticosteroids and immunosuppressants
- Malnutrition, which can affect the body's ability to produce lymphocytes
- Stress, which can temporarily lower lymphocyte levels
Symptoms
The symptoms of lymphocytopenia can vary depending on the underlying cause of the condition. Some people with lymphocytopenia may not have any symptoms, while others may experience:
- Frequent or severe infections
- Fever
- Sweating and chills
- Weight loss
- Fatigue
- Swollen lymph nodes
Diagnosis
Lymphocytopenia is typically diagnosed through a complete blood count (CBC), which measures the number of each type of blood cell in a sample of blood. If the CBC shows a low number of lymphocytes, further tests may be done to determine the cause of the lymphocytopenia.
Treatment
The treatment for lymphocytopenia depends on the underlying cause of the condition. Treatment may involve addressing the underlying cause, such as treating an infection or changing a medication that is causing the lymphocytopenia. In some cases, treatment may involve taking medications to boost the immune system.
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Contributors: Prab R. Tumpati, MD