Lisa Mirabello
American geneticist and epidemiologist
Lisa Mirabello is an American geneticist and epidemiologist known for her research in the field of cancer genetics and epidemiology. She is a senior investigator at the National Cancer Institute (NCI), where she focuses on understanding the genetic factors that contribute to cancer susceptibility and progression.
Education and Early Career
Lisa Mirabello received her undergraduate degree in biology from the University of Pennsylvania. She went on to earn her Ph.D. in genetics from the University of Washington, where she conducted research on the genetic basis of complex diseases. Her early work laid the foundation for her interest in the genetic epidemiology of cancer.
Research Focus
Mirabello's research primarily focuses on the genetic and environmental factors that influence the risk of developing cancer. She has made significant contributions to the understanding of osteosarcoma, a type of bone cancer, and human papillomavirus (HPV)-related cancers. Her work involves large-scale genomic studies to identify genetic variants associated with cancer risk.
Osteosarcoma
In her studies on osteosarcoma, Mirabello has investigated the role of genetic mutations and their impact on the development and progression of this aggressive cancer. Her research has identified several genetic markers that are associated with an increased risk of osteosarcoma, providing insights into potential targets for therapeutic intervention.
HPV-Related Cancers
Mirabello has also conducted extensive research on HPV-related cancers, particularly cervical cancer. Her work has helped to elucidate the genetic factors that contribute to the persistence of HPV infections and the progression to cancer. This research is crucial for developing strategies for prevention and early detection of HPV-related malignancies.
Professional Contributions
As a senior investigator at the NCI, Mirabello collaborates with researchers worldwide to advance the understanding of cancer genetics. She is involved in several international consortia and has published numerous articles in leading scientific journals. Her work is highly regarded in the field of cancer epidemiology.
Awards and Recognition
Lisa Mirabello has received several awards for her contributions to cancer research, including recognition from the American Association for Cancer Research and the National Institutes of Health. Her pioneering work continues to influence the field of genetic epidemiology and cancer prevention.
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Contributors: Prab R. Tumpati, MD