Liquefactive necrosis

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Liquefactive Necrosis

Liquefactive necrosis (pronunciation: li-kwe-fak-tiv ne-kro-sis) is a type of necrosis that results in a transformation of the tissue into a liquid viscous mass.

Etymology

The term 'Liquefactive necrosis' is derived from the Latin words 'liquēre', meaning 'to be liquid' and 'necrosis', meaning 'death of cells or tissues'.

Definition

Liquefactive necrosis is a pathological process which occurs when cells in the tissue die off, causing the tissue to turn into a liquid, pus-like substance. This is often associated with focal bacterial or fungal infections, and can also occur in some cases of brain infarction.

Process

The process of liquefactive necrosis involves the digestion of dead cells, resulting in the transformation of the tissue into a liquid mass. This is often due to the action of hydrolytic enzymes, which are released by dead cells, or by leukocytes in response to inflammation.

Related Terms

  • Necrosis: The death of cells or tissues from severe injury or disease, especially in a localized area of the body.
  • Hydrolytic enzymes: Enzymes that catalyze the hydrolysis of a chemical compound.
  • Leukocytes: White blood cells that are involved in protecting the body against both infectious disease and foreign invaders.
  • Inflammation: A localized physical condition in which part of the body becomes reddened, swollen, hot, and often painful, especially as a reaction to injury or infection.
  • Brain infarction: A type of stroke that occurs when blood supply to the brain is interrupted or reduced, depriving brain tissue of oxygen and nutrients.

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