Levonorgestrel acetate
Levonorgestrel acetate is a synthetic progestogen used in various contraceptive methods. It is a derivative of 19-nortestosterone and is also known as 17α-acetoxy-18-methyl-19-nor-δ4-testosterone.
Chemistry
Levonorgestrel acetate is a synthetic progestogen, specifically a 17α-alkylated 19-nortestosterone derivative. It is structurally related to other 19-nortestosterone progestogens such as norgestrel and norgestimate.
Pharmacology
Levonorgestrel acetate acts primarily by preventing ovulation through the suppression of the gonadotropins luteinizing hormone (LH) and follicle-stimulating hormone (FSH). It also increases the thickness of the cervical mucus, which inhibits sperm penetration and reduces the likelihood of fertilization.
Clinical use
Levonorgestrel acetate is used in a variety of contraceptive methods, including intrauterine devices (IUDs), contraceptive implants, and oral contraceptive pills. It is also used in emergency contraception.
Side effects
Common side effects of levonorgestrel acetate include nausea, breast tenderness, headache, and changes in menstrual bleeding patterns. Less common side effects include mood changes, weight gain, and acne.
See also
This progestogen-related article is a stub. You can help WikiMD by expanding it.
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Contributors: Prab R. Tumpati, MD
