Bisabolol

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Bisabolol

Bisabolol chemical structure

Bisabolol is a natural monocyclic sesquiterpene alcohol that is commonly found in the essential oil of German chamomile (Matricaria chamomilla) and other plants. It is known for its soothing and anti-inflammatory properties, making it a popular ingredient in various skincare and cosmetic products.

Chemical Structure

Bisabolol has a chemical formula of C15H26O and a molecular weight of 222.37 g/mol. Its structure consists of a monocyclic ring with a hydroxyl group (-OH) and an isopropyl group (-CH(CH3)2) attached to it. The compound exists in two enantiomeric forms, namely (+)-α-bisabolol and (-)-α-bisabolol, with the former being the most common and biologically active form.

Properties and Benefits

Bisabolol possesses several beneficial properties that make it a valuable ingredient in various applications. It is known for its anti-inflammatory, anti-irritant, and anti-microbial properties, which make it suitable for use in skincare products. It helps to soothe and calm the skin, reducing redness and irritation. Additionally, bisabolol has been found to have antioxidant properties, which can help protect the skin from damage caused by free radicals.

Furthermore, bisabolol has been studied for its potential anti-cancer properties. Research has shown that it may inhibit the growth of certain cancer cells and induce apoptosis (programmed cell death) in cancer cells, making it a promising compound for further investigation in cancer treatment.

Uses

Bisabolol is widely used in the cosmetic and personal care industry. It is a common ingredient in skincare products such as creams, lotions, and serums, where it helps to soothe and moisturize the skin. It is also used in various cosmetic products, including lipsticks, foundations, and eyeshadows, to provide a smooth and silky texture.

In addition to its skincare applications, bisabolol is also used in oral care products such as toothpaste and mouthwash due to its anti-inflammatory and antimicrobial properties. It can help reduce gum inflammation and promote oral health.

Safety and Precautions

Bisabolol is generally considered safe for topical use in skincare and cosmetic products. However, as with any ingredient, some individuals may experience allergic reactions or skin sensitivities. It is recommended to perform a patch test before using products containing bisabolol, especially for those with sensitive skin.

References


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Contributors: Prab R. Tumpati, MD