Levacetylleucine
A medication used to treat vertigo
| Levacetylleucine | |
|---|---|
| [[File:|frameless|220px|alt=|]] | |
| INN | |
| Drug class | |
| Routes of administration | Oral |
| Pregnancy category | |
| Bioavailability | |
| Metabolism | |
| Elimination half-life | |
| Excretion | |
| Legal status | Rx-only |
| CAS Number | 99-15-0 |
| PubChem | 6100 |
| DrugBank | DB08998 |
| ChemSpider | 5875 |
| KEGG | D07266 |
Levacetylleucine is a medication primarily used in the treatment of vertigo. It is known by the trade name Tanganil. The drug is a derivative of the amino acid leucine, specifically the acetylated form, and is used to alleviate symptoms associated with balance disorders.
Pharmacology
Levacetylleucine works by modulating the activity of the vestibular system, which is responsible for maintaining balance and spatial orientation. The exact mechanism of action is not fully understood, but it is believed to stabilize the function of the vestibular apparatus, thereby reducing the sensation of dizziness and improving balance.
Clinical Use
Levacetylleucine is administered orally and is typically prescribed for patients experiencing acute or chronic vertigo. It is often used in cases where vertigo is a symptom of Meniere's disease, vestibular neuritis, or other disorders affecting the inner ear.
Side Effects
The medication is generally well-tolerated, with few reported side effects. Some patients may experience mild gastrointestinal disturbances, such as nausea or diarrhea. As with any medication, allergic reactions are possible, though rare.
Contraindications
Levacetylleucine should not be used in individuals with known hypersensitivity to the drug or its components. Caution is advised in patients with severe renal or hepatic impairment.
Chemical Properties
Levacetylleucine is a white crystalline powder that is soluble in water. Its chemical formula is C8H15NO3, and it has a molecular weight of 173.21 g/mol. The compound is characterized by the presence of an acetyl group attached to the amino acid leucine.
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Contributors: Prab R. Tumpati, MD
