Keratoglobus

Keratoglobus
Synonyms
Pronounce	N/A
Specialty	N/A
Symptoms	Thinning of the cornea, corneal ectasia, vision impairment
Complications	Corneal rupture, vision loss
Onset	Usually present at birth or develops in early childhood
Duration	Chronic
Types
Causes	Genetic factors, connective tissue disorders
Risks
Diagnosis	Slit-lamp examination, corneal topography
Differential diagnosis	Keratoconus, pellucid marginal degeneration
Prevention
Treatment	Contact lenses, corneal transplantation
Medication
Prognosis	Variable, depending on severity and treatment
Frequency	Rare
Deaths	N/A

Keratoglobus is a rare, non-inflammatory, bilateral eye disorder that results in a generalized thinning and globular protrusion of the cornea. This condition is typically present at birth and is characterized by a round, symmetrically enlarged cornea.

Symptoms

The symptoms of Keratoglobus can vary, but often include:

• Visual impairment
• Photophobia (sensitivity to light)
• Astigmatism
• Myopia (nearsightedness)

Causes

The exact cause of Keratoglobus is unknown, but it is believed to be associated with conditions such as:

• Ehlers-Danlos syndrome
• Blue sclera syndrome
• Marfan syndrome

Diagnosis

Diagnosis of Keratoglobus is typically made through a comprehensive eye examination. This may include:

• Slit lamp examination
• Corneal topography
• Optical coherence tomography

Treatment

Treatment options for Keratoglobus are limited and often challenging due to the thin and fragile nature of the cornea. They may include:

• Contact lenses
• Corneal transplant
• Keratoprosthesis

See also

• Corneal ectasia
• Keratoconus
• Pellucid marginal degeneration

References

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External links

• Keratoglobus at National Center for Biotechnology Information
• Keratoglobus at National Organization for Rare Disorders