Isometamidium chloride
Isometamidium chloride is a chemical compound used primarily in the treatment and prevention of trypanosomiasis, a disease caused by parasitic protozoans belonging to the genus Trypanosoma. It is a member of the phenanthridine class of compounds and is often used in veterinary medicine, particularly in the treatment of livestock.
Chemistry
Isometamidium chloride is a phenanthridine compound. Phenanthridines are a class of heterocyclic compounds that contain a three-ring structure with nitrogen as one of the ring elements. The chemical formula of isometamidium chloride is C28H32Cl3N3O.
Uses
The primary use of isometamidium chloride is in the treatment and prevention of trypanosomiasis in animals. Trypanosomiasis is a disease caused by parasitic protozoans of the genus Trypanosoma, which are transmitted to the host organism through the bite of a tsetse fly. Isometamidium chloride is effective against several species of Trypanosoma, including Trypanosoma congolense and Trypanosoma vivax.
In addition to its use in treating trypanosomiasis, isometamidium chloride is also used in the treatment of babesiosis, a disease caused by parasites of the genus Babesia.
Side Effects
Like all medications, isometamidium chloride can cause side effects. These can include local reactions at the site of injection, such as swelling and pain. Systemic side effects can include fever, loss of appetite, and in rare cases, death.
See Also
References
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Contributors: Prab R. Tumpati, MD