Iridocorneal endothelial syndrome
Iridocorneal Endothelial Syndrome
Iridocorneal Endothelial Syndrome (pronounced as ir-i-do-kor-ne-al en-do-the-li-al sin-drome), often abbreviated as ICE syndrome, is a rare ocular condition that primarily affects the cornea, iris, and endothelium. The etymology of the term is derived from the Greek words 'iris' meaning rainbow, 'keras' meaning horn (cornea), and 'endothelion' meaning inner layer.
Definition
ICE syndrome is a spectrum of diseases characterized by corneal endothelial changes, iris atrophy, and abnormalities of the anterior chamber angle that lead to increased intraocular pressure and glaucoma.
Symptoms
Symptoms of ICE syndrome may include blurred vision, pain in the eye, and the appearance of halos around lights. The condition is often unilateral, affecting only one eye.
Causes
The exact cause of ICE syndrome is unknown. However, it is believed to be due to an abnormal proliferation of corneal endothelial cells that migrate across the anterior chamber angle and onto the surface of the iris.
Diagnosis
Diagnosis of ICE syndrome is typically made based on clinical findings during an eye examination. Additional tests such as gonioscopy, corneal pachymetry, and specular microscopy may also be used.
Treatment
Treatment for ICE syndrome is primarily aimed at controlling the intraocular pressure to prevent or slow the progression of glaucoma. This may involve the use of medications, laser therapy, or surgery.
Related Terms
External links
- Medical encyclopedia article on Iridocorneal endothelial syndrome
- Wikipedia's article - Iridocorneal endothelial syndrome
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