Iobenguane
Iobenguane
Iobenguane (pronunciation: eye-oh-BEN-gwane), also known as MIBG (metaiodobenzylguanidine), is a molecule used in medical imaging to detect certain types of cancer.
Etymology
The term "Iobenguane" is derived from the chemical structure of the compound, which includes iodine (Io), benzene (ben), and guanidine (guane).
Usage
Iobenguane is used in a type of medical imaging called scintigraphy. It is particularly useful in detecting neuroblastoma, a type of cancer that often affects children, and pheochromocytoma, a rare tumor of the adrenal glands. Iobenguane works by mimicking the neurotransmitter norepinephrine, allowing it to be taken up by certain types of cells. This makes these cells visible on a scintigraphy scan.
Related Terms
- Scintigraphy: A diagnostic test in nuclear medicine, where radioisotopes attached to drugs that travel to a specific organ or tissue are taken internally and the emitted gamma radiation is captured by external detectors (gamma cameras) to form images.
- Neuroblastoma: A type of cancer that starts in certain very early forms of nerve cells found in an embryo or fetus.
- Pheochromocytoma: A rare tumor of adrenal gland tissue. It results in the release of too much adrenaline and noradrenaline, hormones that control heart rate, metabolism, and blood pressure.
- Norepinephrine: A neurotransmitter that is important for attentiveness, emotions, sleeping, dreaming, and learning. It is also released as a hormone into the blood, where it causes blood vessels to contract and heart rate to increase.
External links
- Medical encyclopedia article on Iobenguane
- Wikipedia's article - Iobenguane
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