Insulin/IGF/Relaxin family
== Insulin/IGF/Relaxin Family ==
The Insulin/IGF/Relaxin family is a group of peptide hormones that play crucial roles in regulating various physiological processes in the body. This family includes insulin, insulin-like growth factor (IGF), and relaxin hormones. Each member of this family has distinct functions and targets within the body.
Insulin
Insulin is a peptide hormone produced by the pancreas that plays a central role in regulating glucose metabolism. It helps to lower blood glucose levels by promoting the uptake of glucose into cells and the storage of excess glucose as glycogen in the liver and muscles. Insulin also plays a role in protein and fat metabolism.
Insulin-like Growth Factor (IGF)
Insulin-like growth factor (IGF) is a hormone that shares structural similarities with insulin. It is produced in various tissues, including the liver, and plays a key role in promoting cell growth and proliferation. IGF works in conjunction with growth hormone to regulate growth and development in the body.
Relaxin
Relaxin is a peptide hormone that is primarily produced by the ovary and the placenta during pregnancy. It plays a role in the relaxation of the uterus and cervix to facilitate childbirth. Relaxin also has effects on other tissues, including the heart and kidney. The Insulin/IGF/Relaxin family of hormones plays a critical role in maintaining metabolic balance, growth, and reproduction in the body. Dysregulation of these hormones can lead to various health conditions, including diabetes, growth disorders, and reproductive issues.
See Also
- Peptide hormone
- Pancreas
- Glucose metabolism
- Glycogen
- Protein metabolism
- Fat metabolism
- Growth hormone
- Ovary
- Placenta
- Uterus
- Cervix
- Heart
- Kidney
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Contributors: Prab R. Tumpati, MD