Ifetroban

Ifetroban

Ifetroban (pronounced as /ɪˈfɛtroʊbæn/) is a synthetic molecule that acts as a potent and selective antagonist of the thromboxane receptor. It was developed by Cumberland Pharmaceuticals for the treatment of various cardiovascular conditions.

Etymology

The term 'Ifetroban' is derived from the chemical name of the drug, which is 'I'-iso-propyl, 'fet'-fentanyl, 'ro'-rofecoxib, and 'ban'-band. The name signifies the drug's function and its chemical structure.

Pharmacology

Ifetroban works by blocking the thromboxane A2 receptor, thereby inhibiting platelet aggregation and vasoconstriction. This makes it useful in the treatment of conditions such as pulmonary arterial hypertension and hepatorenal syndrome.

Clinical Uses

Ifetroban has been investigated for use in a variety of conditions including:

• Pulmonary arterial hypertension (PAH)
• Hepatorenal syndrome (HRS)
• Cardiovascular disease
• Thrombosis

Side Effects

Like all medications, Ifetroban can cause side effects. These may include:

• Nausea
• Headache
• Dizziness
• Hypotension

See Also

• Thromboxane A2
• Thromboxane receptor
• Cumberland Pharmaceuticals

External links

• Medical encyclopedia article on Ifetroban
• Wikipedia's article - Ifetroban

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