Idiosyncratic drug reaction
Idiosyncratic drug reaction (pronunciation: id-ee-oh-sin-KRAT-ik drug re-AK-shun) is a type of adverse drug reaction that is neither predictable nor dose-dependent. It is an uncommon response to a drug, which is specific to an individual due to genetic differences in metabolism or immune responses.
Etymology
The term "idiosyncratic" is derived from the Greek words "idios" meaning "own, private" and "synkrasis" meaning "mixture". It refers to the unique, individual response a person may have to a drug, which is not seen in the general population.
Types of Idiosyncratic Drug Reactions
Idiosyncratic drug reactions can be classified into two types: type A and type B.
- Type A reaction is predictable, dose-dependent, and is caused by the pharmacological action of the drug.
- Type B reaction is unpredictable, not dose-dependent, and is not related to the pharmacological action of the drug.
Related Terms
- Adverse drug reaction - A harmful or unpleasant reaction, resulting from an intervention related to the use of a medicinal product.
- Pharmacogenomics - The study of how genes affect a person's response to drugs. This relatively new field combines pharmacology (the science of drugs) and genomics (the study of genes and their functions) to develop effective, safe medications and doses that will be tailored to a person's genetic makeup.
- Drug metabolism - The process by which the body breaks down and converts medication into active chemical substances.
See Also
External links
- Medical encyclopedia article on Idiosyncratic drug reaction
- Wikipedia's article - Idiosyncratic drug reaction
This WikiMD dictionary article is a stub. You can help make it a full article.
Languages: - East Asian
中文,
日本,
한국어,
South Asian
हिन्दी,
Urdu,
বাংলা,
తెలుగు,
தமிழ்,
ಕನ್ನಡ,
Southeast Asian
Indonesian,
Vietnamese,
Thai,
မြန်မာဘာသာ,
European
español,
Deutsch,
français,
русский,
português do Brasil,
Italian,
polski